Přehled

The group of Dr. Pavla Perlíková (https://uoch.vscht.cz/research-groups/perlikova-en) at the Department of Organic Chemistry of the University of Chemistry and Technology (UCT) in Prague is looking for a postdoctoral fellow in organic/medicinal chemistry.

Migrastatics represent a new concept of drugs with a great potential to improve the outcome of the current cancer treatment strategies by inhibiting metastatic behavior of cancer cells. Our goal is to use rational design to develop new inhibitors of actin polymerization by targeting the Arp2/3 complex (actin-polymerization nucleator). The project includes a synthesis of hits from virtual screening and its optimization and structure-activity relationship studies. The position is funded by a prestigious Junior STAR grant by the Czech Science Foundation.

We offer:

  • Work in a small team and friendly environment
  • Full-time contract for 12 months with a possibility of extension up to 36 months.
  • Competitive salary (1.2 of the national average)
  • Employee benefits (6 weeks of vacation, catering allowance, language courses, institutional childcare)
  • Low cost of living in tolerant, progressive and secure country with rich cultural and natural heritage
  • Work in the heart of Europe with convenient transport connections to the whole world

We are looking for:

  • Highly motivated postdocs with excellent research experience
  • PhD degree in organic/medicinal chemistry
  • Excellent knowledge of synthetic organic chemistry
  • Track record of publications in peer-reviewed international journals
  • Pro-active, flexible and responsible colleagues willing to supervise younger team members
  • Excellent command of English (level B2 or higher)
  • Organizational, communication and presentation skills

Timelines:

  • Applications will be reviewed on a rolling basis
  • Expected start: January 2025

How to apply:

Please send your CV, a brief motivation letter, at least two reference letters, and a list of publications, togehter with a detailed specification of your personal contribution to the five most important publications, via email to pavla.perlikova@vscht.cz. Applications are accepted until the position is filled. Short-listed candidates will be invited to an online interview.

If not fulfilling some of the requirements but you are enthusiastic to join us, please describe clearly your situation in the cover letter.

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