Overview
Modified 2′-deoxyribonucleoside-triphosphates will be synthesized and used in enzymatic synthesis of oligodeoxyribonucleotides and DNA bearing several modifications at specific positions using a novel approach involving repeated annealing of RNA templates, primer extension and RNA digestion. Applications will include the spatially defined attachment of several different biomolecules, particularly proteins, to DNA.
University:
Faculty of Chemical Technology & Faculty of Food and Biochemical Technology, UCT Prague; Faculty of Science, Charles University
Group:
Michal Hocek Group, Bioorganic and Medicinal Chemistry of Nucleic Acids
Tutor:
Prof. Ing. Michal Hocek, Ph.D. DSc.
Field of study:
Organic chemistry
How to apply:
At the Institute of Organic Chemistry and Biochemistry of the CAS / IOCB Prague, we are looking for talented, independent, and highly motivated PhD students with an MSc. degree or equivalent in life sciences or related fields. We offer exciting new projects in organic and medicinal chemistry, biochemistry, cell biology, molecular and structural biology, and analytical and physical chemistry.
- Online registration deadline: 3 March 2025
- Interview Day: 20 March 2025
Learn more and apply at www.uochb.cz/en/call-for-phd-applications.
