Přehled

What we offer:

A 4-year Ph.D. position in cancer research is available under the Animal Physiology, Immunology, and Developmental Biology program at the Faculty of Science, MUNI, in Brno, Czech Republic. The studentship is funded and includes a part-time grant position. Excellent administrative and technical support is provided.

Who we are looking for:

  • An independent, self-motivated individual with an interest in cell and tumor biology. We are looking forward to it!

Please submit your application before March 31, 2025, here: https://forms.gle/NvD3TNbGMgR4fRJj8

Additional information:

Souček lab: The team’s research focuses on cancer cell plasticity, heterogeneity, and the tumor microenvironment’s role in cancer progression. Cellular plasticity is linked to chemotherapy resistance, recurrence, and poor prognosis, often involving cancer stem-like cells (CSCs/TICs) and circulating tumor cells (CTCs). Evidence suggests that cancer plasticity driven by various stimuli generates CSCs/TICs/CTCs. By studying single cells and their interactions, the group aims to uncover mechanisms behind plasticity and its contribution to cancer progression.

A key new resource is the state-of-the-art BD FACS Discover S8 system, the only one in the country housed at the Institute of Biophysics of the CAS. This advanced technology integrates spectral flow cytometry with sorting and image analysis, enabling precise, high-dimensional profiling of rare cell populations. It facilitates the study of cancer cell plasticity and tumor microenvironment interactions, supporting groundbreaking research into cancer progression and therapy resistance.

Publications: https://orcid.org/0000-0001-7283-8150

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